Multimodal NM encompasses the integration of cerebral physiological parameters that assist intensive care unit (ICU) physicians in the management of brain-injured patients. These parameters include [[intracranial pressure]] (ICP), [[cerebral perfusion pressure]] (CPP), [[cerebral blood flow]] (CBF), [[cerebral oxygenation]], [[cerebral metabolism]], and [[electrocortical activity]] ((Tasneem N, Samaniego EA, Pieper C, et al. Brain multimodality monitoring: a new tool in neurocritical care of comatose patients. Crit Care Res Pract 2017;2017:6097265)).