====== DRESS syndrome ======

Drug [[reaction]] with [[eosinophilia]] and [[systemic]] [[symptom]]s (DRESS) is a type of [[drug]] [[allergy]] that can occur as a [[reaction]] to a large variety of [[medication]]s.

===== Temozolomide-induced DRESS syndrome =====

There are minimal [[report]]s of [[temozolomide]]-induced [[DRESS syndrome]]. The diagnosis can be life-threatening, which makes the [[glioblastoma treatment]] with no alternative treatment option challenging. The use of [[temozolomide desensitization]] has been proposed for the management of severe adverse [[cutaneous drug reaction]]s
((Ambur A, Ambur L, Khan L, Nathoo R. Drug-induced hypersensitivity syndrome following temozolimide for glioblastoma multiforme and the role of desensitization therapy. J Oncol Pharm Pract. 2022 Apr;28(3):733-735. doi: 10.1177/10781552211062569. Epub 2021 Nov 26. PMID: 34825610.)).
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Mehta et al reported a Temozolomide-induced drug rash with eosinophilia and systemic symptoms syndrome
((Mehta H, Gendle CS, Kumaran MS, Vinay K. Temozolomide-induced drug rash with eosinophilia and systemic symptoms syndrome. Indian J Dermatol Venereol Leprol. 2022 Aug 27:1-4. doi: 10.25259/IJDVL_754_2021. Epub ahead of print. PMID: 36332091.)).