====== Dopamine overdose hypothesis ======

Posits that the excess of exogenous [[dopamine]] in the [[frontal]] cortical regions can impair [[cognition]].

Findings demonstrate dopamine-related dissociation in brain activation between cortical and subcortical regions, and provide novel support for the dopamine overdose hypothesis
((Kim J, Zhang K, Cai W, YorkWilliams S, I Ua Cruadhlaoich MA, Llanes S, Menon
V, Poston KL. Dopamine-Related Dissociation of Cortical and Subcortical Brain
Activations in Cognitively Unimpaired Parkinson's Disease Patients OFF and ON
Medications. Neuropsychologia. 2018 Jul 21. pii: S0028-3932(18)30377-4. doi:
10.1016/j.neuropsychologia.2018.07.024. [Epub ahead of print] PubMed PMID:
30040957.
)).