Although the principal attention in the field of cancer has been directed at the phenomenon of [[hypermethylation]], a hallmark of the methylation pattern in many tumours is [[hypomethylation]].

An increase in the [[epigenetic]] [[methylation]] of [[cytosine]] and [[adenosine]] residues in [[DNA]].

Local [[DNA hypermethylation]] is a potential source of [[cancer biomarker]]s.