====== 🩸 Delayed Bleeding ====== **Delayed bleeding** refers to hemorrhagic events that occur **hours to days after the initial trauma, surgery, or vascular event**, often when the patient is clinically stable or discharged. ===== 🧠 Definition ===== A bleeding episode that is **not present on initial imaging or physical exam**, but appears **after a latent period**, frequently requiring **repeat imaging**, **reintervention**, or **close clinical observation**. ===== ⏱️ Typical Timeframes ===== * Within **6–72 hours** after: * **Mild traumatic brain injury** (especially in anticoagulated patients) * **Cranial or spinal surgery** * **Endovascular procedures** * **Biopsies or shunt placements** ===== ⚠️ Risk Factors ===== * Anticoagulant or antiplatelet therapy * Advanced age (>75 years) * Renal failure (affects drug clearance) * Inadequate intraoperative hemostasis * Unrecognized vascular anomalies ===== 🧠 Neurosurgical Context ===== * **Delayed intracranial hemorrhage** after a normal initial CT in mild TBI * **Epidural or subdural rebleeding** after surgical evacuation * **Delayed hemorrhage in tumor bed** post-craniotomy * **Spinal epidural hematoma** after lumbar puncture or decompression ===== 🩻 Management ===== * Maintain **high index of suspicion** if symptoms recur (headache, confusion, vomiting, focal signs) * Repeat **cranial imaging** (usually non-contrast CT) * Consider ICU observation for high-risk patients even with normal initial imaging * Surgical or endovascular intervention if mass effect or clinical deterioration ===== ✅ Best Practice ===== * Clearly document bleeding risk and timing of last anticoagulant dose * Inform patients and families about **symptoms of delayed bleeding** * Schedule structured follow-up or control imaging in high-risk scenarios ===== 🔗 Related Entries ===== * [[clinical_deterioration]] * [[anticoagulation_reversal_protocol]] * [[dabigatran_reversal_in_mild_traumatic_brain_injury]] * [[postoperative_complications]]