=====Cranial wound===== Complex cranial wounds can be a problematic occurrence for surgeons. These can result from trauma, infection, malignancy, wound break down, and radiation ((Powers AK, Neal MT, Argenta LC, Wilson J, DeFranzo AJ, Tatter SB. Vacuum-assisted closure for complex cranial wounds involving the loss of dura mater. J Neurosurg. 2003;118:302–8.)). see [[Wound reconstruction]] see [[Vacuum assisted closure]]