====== Conivaptan ====== (Vaprisol®): a nonpeptide antagonist of V1A & V2 [[vasopressin receptor]]s. [[FDA]] approved for euvolemic and hypervolemic moderate-to-severe [[hyponatremia]] in hospitalized patients (NB: severe symptoms of seizures, coma, [[delirium]]…warrants [[aggressive treatment]] with [[hypertonic saline]] ((Ellison DH, Berl T. Clinical practice. The syndrome of inappropriate antidiuresis. N Engl J Med. 2007; 356:2064–2072))).