====== Conditions associated with aneurysms ======

Conditions associated with [[aneurysm]]s

1. [[autosomal dominant polycystic kidney disease]]: 

2. [[fibromuscular dysplasia]] (FMD): prevalence of [[aneurysm]]s in renal FMD is 7%, in aortocranial
FMD 21%

3. [[arteriovenous malformation]]s (AVM) including [[moyamoya disease]]

4. [[connective tissue disease]]s:

a) Ehlers-Danlos, especially type IV (deficient collagen type III)which also has a high rate of arterial dissection, including with angiography or coiling

b) [[Marfan syndrome]]

c) [[pseudoxanthoma elasticum]]

5. multiple other family members with [[intracranial aneurysm]]s. Familial intracranial aneurysm
syndrome (FIA): 2 or more relatives, third-degree or closer, harbor radiographically proven
intracranial aneurysms.

6. [[coarctation of the aorta]]
((Bigelow NH. The association of polycystic kidneys with intracranial aneurysms and other related dis- orders. Am J Med Sci. 1953; 225:485–494))

7. [[hereditary hemorrhagic telangiectasia]]
((Maher CO, Piepgras DG, Brown RD,Jr, et al. Cerebrovascular manifestations in 321 cases of hereditary hemorrhagic telangiectasia. Stroke. 2001; 32:877–882)) 
([[Osler-Weber-Rendu syndrome]])

8. [[atherosclerosis]]
((Longstreth WT, Koepsell TD, Yerby MS, et al. Risk Factors for Subarachnoid Hemorrhage. Stroke. 1985; 16:377–385)).

9. [[bacterial endocarditis]]

10. [[multiple endocrine neoplasia type 1]] 
((Schievink WI. Genetics and aneurysm formation. Neurosurg Clin N Am. 1998; 9:485–495)).

11. [[neurofibromatosis type 1]] 
((Schievink WI, Riedinger M, Maya MM. Frequency of incidental intracranial aneurysms in neurofi- bromatosis type 1. Am J Med Genet A. 2005; 134A: 45–48)).
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Aneurysms associated with arteriovenous malformations (AVM) are well represented in the literature. Their exact etiology is poorly understood, but likely global hemodynamic changes coupled with vascular wall pathology play into their formation. Flow-related and intranidal aneurysms, in particular, appear to have an increased risk for hemorrhagic presentation. Treatment strategies for these aneurysms are particularly challenging
((He L, Gao J, Thomas AJ, Fusco MR, Ogilvy CS. Disappearance of a ruptured
distal flow-related aneurysm after AVM nidal embolization. World Neurosurg. 2015 
Jun 10. pii: S1878-8750(15)00714-7. doi: 10.1016/j.wneu.2015.05.065. [Epub ahead 
of print] PubMed PMID: 26072456.
)).