====== Complement factor I ======
Mutations in the complement factor I (CFI) [[gene]] have previously been identified as causes of recurrent [[Neuroinflammation]]. 
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We present a case of a 26-year-old man with 18 episodes of recurrent meningitis, who had a variant in CFI(c.859G>A,p.Gly287Arg) not previously associated with neurologic manifestations. He achieved remission with canakinumab, a human monoclonal antibody targeted at interleukin-1 beta.