====== Clinical study ======

[[Research]] or a detailed examination and analysis of a subject.

===== Design =====
see [[Clinical study design]].

===== Classification =====
[[Cohort]] study

[[Double blind study]]

[[Multicenter]] [[research trial]]

[[Placebo controlled study]]

[[Prospective]] study

[[Randomized controlled trial]]

[[Retrospective study]].
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[[Research]]

An experiment
In particular, a [[clinical trial]].

[[Experimental study]]

[[Observational trial]]

[[Preliminary study]]

[[Retrospective study]]


Studies ([[journal]])

see [[imaging study]]

see [[clinical trial]]
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Vargas-Caballero et al suggest that replicating elements of research findings from [[animal]]s and [[stem cell]] models in resected human [[brain tissue]] would strengthen our understanding of disease mechanisms and the therapeutic strategies and aid translation. 
The use of human brain tissue alongside induced [[pluripotent stem cell]]s iPSC-derived neural models can validate molecular mechanisms identified in rodent disease models and strengthen their relevance to humans. If drug target engagement and mechanism of cellular action can be validated in human brain tissue, this will increase the success rate in clinical research. The combined use of resected human brain tissue, alongside iPSC-derived neural models, could be considered a standard step in pre-clinical research and help to bridge the gap to [[clinical trial]]s
((Vargas-Caballero M, Willaime-Morawek S, Gomez-Nicola D, Perry VH, Bulters D,
Mudher A. The use of human neurons for novel drug discovery in dementia research.
Expert Opin Drug Discov. 2016 Feb 15. [Epub ahead of print] PubMed PMID:
26878555.
)).