====== Clear cell renal carcinoma intracranial metastases ======

{{rss>https://pubmed.ncbi.nlm.nih.gov/rss/search/1tuP1jHjERT3Y4Gs80R9hjnNubZq_Wk170DfwRrvJDNhZT7Q7j/?limit=15&utm_campaign=pubmed-2&fc=20241009113617}}
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see also [[Renal cell carcinoma intracranial metastases]].

see [[Clear cell renal carcinoma brain metastases]]



====== Case reports ======


A 59-year-old female patient presented with medullary syndrome. There was a previous history of VHLd, with a [[cerebellar hemangioblastoma]] resection years ago. The radiological investigation showed a cervical intramedullary solid-cystic lesion. The patient has submitted a tumor resection, and a pathological and immunohistochemistry study confirmed clear cell renal carcinoma metastasis.

In patients with VHLd, the presence of an intramedullary solid-cystic lesion may not represent always a hemangioblastoma. Other diagnostic possibilities must be evaluated, despite being epidemiologically less frequent. Inside the group of patients with VHLd, only a previous case of intramedullary spinal cord renal cell carcinoma was reported in the literature
((Holanda TSF, Lopes E Jr. Intramedullary spinal cord metastasis of clear cell renal carcinoma in a Von Hippel-Lindau patient. Surg Neurol Int. 2022 Oct 28;13:491. doi: 10.25259/SNI_298_2022. PMID: 36447864; PMCID: PMC9699871.)).