====== Choroid plexus carcinoma outcome ======

3 and 5-year [[progression-free survival]] rates are 58% and 38% respectively, and [[overall survival]] is 83% and 62% for the same time periods.

Absence of [[TP53 mutation]] may be associated with a more favorable outcome. One study showed a worse outome in tumors with loss of chromosome arm 12q
((Ruland V, Hartung S, Kordes U, et al. Choroid plexus carcinomas are characterized by complex chromo- somal alterations related to patient age and progno- sis. Genes Chromosomes Cancer. 2014; 53:373–380)).
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The pediatric proclivity, in combination with a marked vascularity, renders an aggressive resection a difficult and often dangerous endeavor, with few treatment options.

Gross total resection is the most consistent predictor of survival
((Kubicky CD, Sahgal A, Chang EL, Lo SS. Rare primary central nervous system tumors. Rare Tumors. 2014 Aug 4;6(3):5449. doi: 10.4081/rt.2014.5449. eCollection 2014 Jul 30. Review. PubMed PMID: 25276324; PubMed Central PMCID: PMC4178277.)).