====== Cerebral blood volume ======
150 ml.

Quantitative measurement of [[cerebral]] [[blood]] [[volume]] (CBV, defined as ml blood in 100 ml brain) is useful for advancing our understanding of [[brain physiology]] and [[pathophysiology]]
((Derdeyn CP, Videen TO, Yundt KD, Fritsch SM, Carpenter DA, Grubb RL, Powers WJ. Variability of cerebral blood volume and oxygen extraction: stages of cerebral hemodynamic impairment revisited. Brain. 2002;125(Pt 3):595–607.))
((Kavec M, Usenius JP, Tuunanen PI, Rissanen A, Kauppinen RA. Assessment of cerebral hemodynamics and oxygen extraction using dynamic susceptibility contrast and spin echo blood oxygenation level-dependent magnetic resonance imaging: applications to carotid stenosis patients. Neuroimage. 2004;22:258–267)).
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[[Perfusion computed tomography]] (CT) is a technique that allows rapid qualitative and quantitative evaluation of [[cerebral perfusion]] by generating maps of [[cerebral blood flow]] (CBF), [[cerebral blood volume]] (CBV), and [[mean transit time]] (MTT).

see [[Relative cerebral blood volume]].
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Studies found significantly higher median CBV (p = 0.00003, ANOVA) and lower median ADC in contrast-enhancing areas of glioblastomas, compared to astrocytomas and oligodendrogliomas (p = 0.41333, ANOVA). Interestingly, molecularly defined glioblastoma, which usually does not contain contrast-enhancing areas, also shows significantly higher CBV values in the non-enhancing tumor than common glioblastoma and astrocytoma grade 4 (p = 0.01309, ANOVA).

Advanced imaging shows promise in visualizing tumor biology and improving the diagnosis of brain tumor patients
((Griessmair M, Delbridge C, Ziegenfeuter J, Bernhardt D, Gempt J, Schmidt-Graf F, Kertels O, Thomas M, Meyer HS, Zimmer C, Meyer B, Combs SE, Yakushev I, Wiestler B, Metz MC. Imaging the WHO 2021 Brain Tumor Classification: Fully Automated Analysis of Imaging Features of Newly Diagnosed Gliomas. Cancers (Basel). 2023 Apr 18;15(8):2355. doi: 10.3390/cancers15082355. PMID: 37190283.))