Calmodulin-binding proteins are, as their name implies, proteins which bind calmodulin. Calmodulin can bind to a variety of proteins through a two-step binding mechanism "conformational and mutually induced fit", where typically two domains of calmodulin wrap around an emerging helical calmodulin binding domain from the target protein. ====== Examples ====== Gap-43 protein (presynaptic) [[Neurogranin]] (postsynaptic) Caldesmon