The clinical [[Deep-Vein Thrombosis diagnosis]] is very unreliable. A patient with the “classic signs” of a hot, swollen, and tender [[calf]] or a positive [[Homans’ sign]] ([[calf pain]] on dorsiflexion of the [[ankle]]) will have a Deep-vein thrombosis only 20–50% of the time
((Hamilton MG, Hull RD, Pineo GF. [[Venous Thromboembolism]] in Neurosurgery and Neurology Patients: A Review. Neurosurgery. 1994; 34:280–296)).
50–60% of patients with Deep-vein thrombosis will not have these findings.