====== Ca15-3 ====== Ca15-3 is the protein product of the [[MUC1]] gene and is the most widely used serum marker in [[breast cancer]]. There was a decrease in [[HIF1A]], followed by a decrease in [[Ca15-3]] and [[RECIST]] in response to [[chemotherapy]]. There was a statistically significant correlation between Ca15-3 and response to chemotherapy ((Manginstar C, Oley MH, Oley MC, Merung M, Langi FLFG, Kepel BJ, Rusli LV, Islam AA, Faruk M. Correlation analysis of HIF-1α and Ca15-3 in response to neoadjuvant chemotherapy in locally advanced breast cancer: A cohort study in Indonesia. Breast Dis. 2022;41(1):481-487. doi: 10.3233/BD-229004. PMID: 36641657.)).