===== C57BL/6 (WT) Mice =====

**C57BL/6 mice** (commonly known as **Black 6**) are the most widely used inbred mouse strain in biomedical research.

=== Key Characteristics ===
  * 🧬 **Inbred strain** – genetically homogeneous
  * 🐭 **Black fur**, calm behavior
  * 🔬 Common background for genetically engineered models

=== What does WT mean? ===
  * **WT** stands for **Wild-Type**
  * Mice that do not carry any gene modifications
  * Serve as control group in experimental research

=== Scientific Uses ===
  * Baseline for knockout/knock-in comparisons (e.g., AQP3⁻/⁻)
  * Immunology, neurology, oncology, and metabolism studies
  * Extensive availability and reference data

=== External Resources ===
  * [[https://www.jax.org/strain/000664|The Jackson Laboratory – C57BL/6J]]
  * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810327/|C57BL/6 background: strengths and limitations]]