====== Blood component therapy ======

===== Massive transfusions =====

Definition: [[replacement]] of > 1 blood volume (in average adult ≈ 20 U) in < 24 hrs for adults, or > 2 × circulating blood volume in peds, may cause dilution of effective platelets and [[coagulation factors]],
which requires [[platelet transfusion]] and [[fresh frozen plasma]] (FFP). When operating on a pediatric patient, you can usually safely replace up to 1.5 × the circulating blood volume before problems with
[[coagulopathy]] ensue.
----

Blood component therapy required for massive [[transfusion]]s:

[[Red blood cell]] therapy