====== Bias Assessment Tool ====== A **[[bias]] [[assessment tool]]** is a standardized [[instrument]] used to evaluate the **[[bias risk]]** in individual studies included in a [[systematic review]] or [[meta-analysis]]. These [[tool]]s help reviewers judge the internal validity of studies and assess how much trust can be placed in their results. === Purpose === * Identify potential sources of systematic error * Grade the **quality** and **credibility** of included studies * Support transparent, evidence-based conclusions === Commonly Used Tools === ^ Tool ^ Target Study Design ^ Description ^ | [[rob1|Cochrane RoB 1]] | Randomized Controlled Trials (RCTs) | Assesses seven domains of bias (e.g., selection, performance, detection) | | [[rob2|Cochrane RoB 2]] | RCTs (updated version) | Focuses on bias at the outcome level; structured judgments with signalling questions | | [[robins_i|ROBINS-I]] | Non-randomized studies | Evaluates bias across seven domains before and after intervention | | [[newcastle_ottawa_scale|Newcastle-Ottawa Scale]] | Observational studies | Assesses selection, comparability, and outcome/exposure | | [[amstar2|AMSTAR 2]] | Systematic reviews | Appraisal of reviews' methodological quality, especially in healthcare |