The [[Autophagy]]-related genes (Atg), characterized extensively in yeast, are a set of approximately twenty evolutionarily conserved genes required for autophagy. Autophagy (specifically, macroautophagy) is the process of bulk degradation of cytoplasmic material.
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The [[methylation]] levels of 6 [[autophagy-related genes]] (ARGs) ([[ARSB]], [[CFLAR]], [[WIPI2]], [[RB1]], [[ERN1]], [[RAB24]]) have a strong predictive potential for LGG, and the methylation regulation of ARGs has an important impact on the immune microenvironment of LGGs.