====== Angiopoietin ======

Angiopoietin is part of a family of [[vascular endothelial growth factor]]s that play a role in embryonic and postnatal [[angiogenesis]]. Angiopoietin signaling most directly corresponds with angiogenesis.

Angiopoietin cytokines are involved with controlling microvascular permeability, vasodilation, and vasoconstriction by signaling smooth muscle cells surrounding vessels.

[[Angiopoietin]]s play a pivotal role in tumor angiogenesis by modulating vascular endothelial proliferation and survival. The expression of angiopoietin 1 and [[angiopoietin 2]] (Ang-1 and Ang-2) and vascular endothelial growth factor (VEGF) has been documented in human malignant glioma.