====== Aggressiveness ====== Spreading rapidly or highly invasive; difficult or impossible to treat successfully. Aggressiveness has a high prevalence in psychiatric patients and is a major health problem. Two brain areas involved in the neural network of aggressive behavior are the [[amygdala]] and the [[hypothalamus]]. While pharmacological treatments are effective in most patients, some do not properly respond to conventional therapies and are considered medically [[refractory]]. see [[Refractory aggressiveness]].