====== Adult brainstem glioma treatment ====== Conventional [[radiotherapy]] for Adult [[brainstem glioma treatment]] is the standard treatment for diffuse intrinsic low-grade brainstem gliomas in adults (the median survival is 5 years). In malignant brainstem gliomas, [[radiotherapy]] is the standard treatment. However, the possible benefit of combined [[radiotherapy]] and [[chemotherapy]] ([[temozolomide]] or other agents) has not been thoroughly evaluated in adults. The role of anti-angiogenic therapies in [[brainstem glioma]]s remains to be defined. A better understanding of the biology of these tumors is of primary importance for identifying homogeneous subgroups and for improving therapy options and outcomes ((Reyes-Botero G, Mokhtari K, Martin-Duverneuil N, Delattre JY, Laigle-Donadey F. Adult brainstem gliomas. Oncologist. 2012;17(3):388-97. doi: 10.1634/theoncologist.2011-0335. Epub 2012 Mar 1. Review. PubMed PMID: 22382458; PubMed Central PMCID: PMC3316925. )).