====== 1998 ====== [[1997]]-[[1999]] First therapeutic report of [[temozolomide]] to treat human [[glioma]]s ((Friedman HS, McLendon RE, Kerby T, et al. [[DNA mismatch repair]] and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol 1998;16: 3851–7)). ---- Intraosseous nerves within the vertebral body were described in 1998 by Antonacci et al ((Antonacci MD, Mody DR, Heggeness MH. Innervation of the human vertebral body: a histologic study. J Spinal Disord. 1998 Dec;11(6):526-31. PubMed PMID: 9884299.)). ---- In [[1998]], a group led by Dr. Jerry Oakes ((Iskandar BI, Hedlund GL, Grabb PA, Oakes WJ. The resolution of syringomyelia without hindbrain herniation after posterior fossa decompression. J Neurosurg 1998;89: 212–216.)) identified five patients with [[syringomyelia]] and no evidence of [[tonsillar herniation]] (i.e. no Chiari I malformation). ---- [[Medtronic]] aquired [[Sofamor]] [[Danek]] in [[1998]]. ---- Vicari in [[1994]] ((Vicari F Endoscopic correction of sagittal craniosynostosis Paper presented at: Meeting of the American Society of Plastic Surgeons; September 25–28, 1994; San Diego, CA)) and Drs. Barone and Jimenez in [[1998]] ((Jimenez DF, Barone CM. Endoscopic craniectomy for early surgical correction of sagittal craniosynostosis. J Neurosurg. 1998 Jan;88(1):77-81. PubMed PMID: 9420076. )) introduced [[endoscopic-assisted craniosynostosis surgery]] followed by application of a molding helmet.