====== 1952 ====== [[1951]]-[[1953]] The use of [[corticosteroid]]s to treat cerebral [[edema]] in [[brain tumor]] patients dates back to case reports by Ingraham and Matson in [[1952]] ((Ingraham FD, Matson DD, Mc LR. Cortisone and ACTH as an adjunct to the surgery of craniopharyngiomas. N Engl J Med. 1952;246(15):568–571.)). ---- Intra-arterial (IA) delivery of chemotherapeutic agents for brain tumors was introduced as a therapeutic option as far back as [[1950]] by Klopp et al in animals ((Klopp CT, Alford TC, Bateman J, et al. Fractionated intra-arterial cancer. chemotherapy with methyl bis amine hydrochloride; a preliminary report. Ann Surg 1950;132:811–32.)) and [[1952]] by French et al in humans ((French JD, West PM, von Amerongen FK, et al. Effects of intracarotid administration of nitrogen mustard on normal brain and brain tumors. J Neurosurg 1952;9:378–89.)). ---- Love and Dodge ((LOVE JG, DODGE HW Jr. Dumbbell (hourglass) neurofibromas affecting the spinal cord. Surg Gynecol Obstet. 1952 Feb;94(2):161-72. PubMed PMID: 14901250.)) in 1952 first coined the term [[dumbbell tumor]], reporting a neurogenic tumor with in growths into the spinal canal. In addition, these tumors may grow extensively outside the spinal canal and compress the paraspinal-iliopsoas complexes as well as retroperitoneal vascular structures. ---- In [[1952]], it was at [[Sainte-Anne Hospital]] that Jean Delay and Pierre Deniker used the first neuroleptic, chlorpromazine, to cure psychiatric patients, putting an end to the expansion of [[psychosurgery]]. ---- [[James Watson Kernohan]] has been recognized as the first neurosurgeon to report an intramedullary schwannoma case in [[1952]], though [[Wilder Penfield]] had already described an [[intramedullary]] lesion with [[schwannoma]]s characteristics in [[1932]] ((Penfield W. Notes on operative technic in neurosurgery. Ann surg. 1946;124:383–5.)). ---- [[Baylor College of Medicine]] Department of Neurosurgery was established in [[1952]] as a division of the Department of Surgery, and is led by department chair, Dr. Daniel Yoshor.