====== 1886 ====== [[1885]]-[[1887]] Carlo Giacomini was the first to describe the os odontoideum in [[1886]] and to suggest that the presence of an incompetent [[odontoid process]] may alter the motion of [[craniovertebral junction]], anticipating the concept of [[spine instability]] ((Perrini P, Montemurro N, Iannelli A. The contribution of Carlo Giacomini (1840-1898): the limbus Giacomini and beyond. Neurosurgery. 2013 Mar;72(3):475-81; discussion 481-2. doi: 10.1227/NEU.0b013e31827fcda3. PubMed PMID: 23208067.)). ---- Awake [[craniotomy]] (AC) was first performed by Sir [[Victor Horsley]] in [[1886]] to localise the epileptic focus with [[cortical]] [[electrostimulation]] ((Piccioni F, Fanzio M. Management of anesthesia in awake craniotomy. Minerva Anestesiol. 2008 Jul-Aug;74(7-8):393-408. PMID: 18612268.)). ---- [[Georg Thieme]] Verlag was founded in [[1886]] in Leipzig, Germany, by [[Georg Thieme]] when he was 26 years old. Thieme remains privately held and family-owned. The company received some early success in [[1896]] by publishing Wilhelm Röntgen's famous picture of his wife's hand in what is still one of Thieme's and Germany's oldest journals, the Deutsche Medizinische Wochenschrift. In 1919, Georg Thieme partnered with Bruno Hauff, a young publisher from Leipzig. When Thieme died in 1925, ownership of the company passed to Hauff. Members of the Hauff family have been the proprietors of the business ever since. In 1946, two years after Thieme had been bombed and forced to close completely during World War II, the Allies relocated the company from Leipzig in the eastern sector to [[Stuttgart]] in the west where it was provided with a license to publish and distribute journals, brochures, and books. Guenther Hauff, son of Bruno, acquired Stratton International Medical Book of New York in 1979, and several years later, in 1984, the two companies merged to become Thieme Medical Publishers New York.