[[GFAP]] is a type III [[intermediate filament]] (IF) protein that maps, in humans, to [[17q21]]. 7q21.31 [[microdeletion syndrome]], also known as Koolen–de Vries syndrome (KdVS), is a rare genetic disorder caused by a deletion of a segment of chromosome 17 which contains six genes. This deletion syndrome was discovered independently in 2006 by three different research groups.