WHO classification of tumors of hematopoietic and lymphoid tissues [Neurosurgery Wiki]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
====== WHO classification of tumors of hematopoietic and lymphoid tissues ======

Myeloid neoplasms

myeloproliferative neoplasms

chronic myeloid leukemia, BCR-ABL1-positive

chronic neutrophilic leukemia

[[polycythemia vera]]

primary myelofibrosis
essential thrombocythemia
chronic eosinophilic leukemia, not otherwise specified
myeloproliferative neoplasm, unclassifiable
mastocytosis
cutaneous mastocytosis
systemic mastocytosis
indolent systemic mastocytosis
smoldering systemic mastocytosis
systemic mastocytosis with an associated hematological neoplasm
aggressive systemic mastocytosis
mast cell leukemia
mast cell sarcoma
myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement
myeloid/lymphoid neoplasms with PDGFRA rearrangement
myeloid/lymphoid neoplasms with PDGFRB rearrangement
myeloid/lymphoid neoplasms with FGFR1 rearrangement
myeloid/lymphoid neoplasms with PCM1-JAK2 (provisional entity)
myelodysplastic/myeloproliferative neoplasms
chronic myelomonocytic leukemia
atypical chronic myeloid leukemia, BCR-ABL1-negative
juvenile myelomonocytic leukemia
myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis
myelodysplastic/myeloproliferative neoplasm, unclassifiable
myelodysplastic syndromes
myelodysplastic syndrome with single lineage dysplasia
myelodysplastic syndrome with multilineage dysplasia
myelodysplastic syndrome with ring sideroblasts
myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia
myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia
myelodysplastic syndrome with excess blasts
myelodysplastic syndrome with isolated del(5q)
myelodysplastic syndrome, unclassifiable
refractory cytopenia of childhood (provisional entity)
myeloid neoplasms with germline predisposition
myeloid neoplasms with germline predisposition without a preexisting disorder or organ dysfunction
acute myeloid leukemia with germline CEBPA mutation
myeloid neoplasms with germline DDX41 mutation
myeloid neoplasms with germline predisposition and preexisting platelet disorders
myeloid neoplasms with germline RUNX1 mutation
myeloid neoplasms with germline ANKRD26 mutation
myeloid neoplasms with germline ETV6 mutation
myeloid neoplasms with germline predisposition and other organ dysfunction
myeloid neoplasms with germline GATA2 mutation
myeloid neoplasms associated with bone marrow failure syndromes
myeloid neoplasms associated with telomere biology disorders
juvenile myelomonocytic leukemia associated with neurofibromatosis, Noonan syndrome or Noonan syndrome-like disorders
myeloid neoplasms associated with Down syndrome
acute myeloid leukemia and related neoplasms
acute myeloid leukemia with recurrent genetic abnormalities
acute myeloid leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1
acute myeloid leukemia with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
acute promyelocytic leukemia with PML-RARA
acute myeloid leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A
acute myeloid leukemia with t(6;9)(p23;q34.1); DEK-NUP214
acute myeloid leukemia with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2); GATA2, MECOM
acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13.3;q13.3); RBM15-MKL1
acute myeloid leukemia with BCR-ABL1 (provisional entity)
acute myeloid leukemia with mutated NPM1
acute myeloid leukemia with biallelic mutations of CEBPA
acute myeloid leukemia with mutated RUNX1 (provisional entity)
acute myeloid leukemia with myelodysplasia-related changes
therapy-related myeloid neoplasms
acute myeloid leukemia, not otherwise specified
acute myeloid leukemia with minimal differentiation
acute myeloid leukemia without maturation
acute myeloid leukemia with maturation
acute myelomonocytic leukemia
acute monoblastic/monocytic leukemia
pure erythroid leukemia
acute megakaryoblastic leukemia
acute basophilic leukemia
acute panmyelosis with myelofibrosis
myeloid sarcoma
myeloid proliferations related to Down syndrome
transient abnormal myelopoiesis
myeloid leukemia associated with Down syndrome
blastic plasmacytoid dendritic cell neoplasm
acute leukemias of ambiguous lineage
acute undifferentiated leukemia
mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1
mixed phenotype acute leukemia with t(v;11q23.3); KMT2A rearranged
mixed phenotype acute leukemia, B/myeloid, not otherwise specified
mixed phenotype acute leukemia, T/myeloid, not otherwise specified
Lymphoid neoplasms
precursor lymphoid neoplasms
B-lymphoblastic leukemia/lymphoma
B-lymphoblastic leukemia/lymphoma, not otherwise specified
B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2); BCR-ABL1
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3); KMT2A rearranged
B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1
B-lymphoblastic leukemia/lymphoma with hyperdiploidy
B-lymphoblastic leukemia/lymphoma with hypodiploidy
B-lymphoblastic leukemia/lymphoma with t(5;14)(q31.1;q32.3); IL3-IGH
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1
B-lymphoblastic leukemia/lymphoma, BCR-ABL1–like (provisional entity)
B-lymphoblastic leukemia/lymphoma with iAMP21 (provisional entity)
T-lymphoblastic leukemia/lymphoma
early T-cell precursor lymphoblastic leukemia (provisional entity)
natural killer (NK) cell lymphoblastic leukemia/lymphoma (provisional entity)
mature B-cell neoplasms
chronic lymphocytic leukemia/small lymphocytic lymphoma
monoclonal B-cell lymphocytosis
B-cell prolymphocytic leukemia
splenic marginal zone lymphoma
hairy cell leukemia
splenic B-cell lymphoma/leukemia, unclassifiable
splenic diffuse red pulp small B-cell lymphoma (provisional entity)
hairy cell leukemia-variant (provisional entity)
lymphoplasmacytic lymphoma
Waldenström macroglobulinemia
IgM monoclonal gammopathy of undetermined significance
heavy-chain diseases
μ heavy-chain disease
γ heavy-chain disease
α heavy-chain disease
plasma cell neoplasms
non-IgM monoclonal gammopathy of undetermined significance (IgG/A)
plasma cell myeloma (a.k.a. multiple myeloma)
plasma cell myeloma variants
smoldering (asymptomatic) plasma cell myeloma
non-secretory myeloma
plasma cell leukemia
plasmacytoma
solitary plasmacytoma of bone
extraosseous plasmacytoma
monoclonal immunoglobulin deposition diseases
primary amyloidosis
light chain and heavy chain deposition diseases
plasma cell neoplasms with associated paraneoplastic syndrome
POEMS syndrome
TEMPI syndrome
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
nodal marginal zone lymphoma
pediatric nodal marginal zone lymphoma (provisional entity)
follicular lymphoma
testicular follicular lymphoma
in situ follicular neoplasia
duodenal-type follicular lymphoma
pediatric-type follicular lymphoma
large B-cell lymphoma with IRF4 rearrangement (provisional entity)
primary cutaneous follicle center lymphoma
mantle cell lymphoma
leukemic non-nodal mantle cell lymphoma
in situ mantle cell neoplasia
diffuse large B-cell lymphoma, not otherwise specified
germinal center B-cell type
activated B-cell type
T-cell/histiocyte-rich large B-cell lymphoma
primary diffuse large B-cell lymphoma of the central nervous system
primary cutaneous diffuse large B-cell lymphoma, leg type
EBV-positive diffuse large B-cell lymphoma, not otherwise specified
EBV-positive mucocutaneous ulcer (provisional entity)
diffuse large B-cell lymphoma associated with chronic inflammation
fibrin-associated diffuse large B-cell lymphoma
lymphomatoid granulomatosis
primary mediastinal (thymic) large B-cell lymphoma
intravascular large B-cell lymphoma
----

[[ALK-positive large B-cell lymphoma]]
----

plasmablastic lymphoma
primary effusion lymphoma
HHV8-associated lymphoproliferative disorders
multicentric Castleman disease
HHV8-positive diffuse large B-cell lymphoma, not otherwise specified (provisional entity)
HHV8-positive germinotropic lymphoproliferative disorder
Burkitt lymphoma
Burkitt-like lymphoma with 11q aberration (provisional entity)
high-grade B-cell lymphoma
high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements
high-grade B-cell lymphoma, not otherwise specified
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma
mature T- and NK-cell neoplasms
T-cell prolymphocytic leukemia
T-cell large granular lymphocytic leukemia
chronic lymphoproliferative disorder of NK cells (provisional entity)
aggressive NK-cell leukemia
EBV-positive T-cell and NK-cell lymphoproliferative diseases of childhood
systemic EBV-positive T-cell lymphoma of childhood
chronic active EBV infection of T- and NK-cell type, systemic form
hydroa vacciniforme–like lymphoproliferative disorder
severe mosquito bite allergy
adult T-cell leukemia/lymphoma
extranodal NK-/T-cell lymphoma, nasal type
intestinal T-cell lymphoma
enteropathy-associated T-cell lymphoma
monomorphic epitheliotropic intestinal T-cell lymphoma
intestinal T-cell lymphoma, not otherwise specified
indolent T-cell lymphoproliferative disorder of the gastrointestinal tract (provisional entity)
hepatosplenic T-cell lymphoma
subcutaneous panniculitis-like T-cell lymphoma
mycosis fungoides
Sézary syndrome
primary cutaneous CD30+ T-cell lymphoproliferative disorders
lymphomatoid papulosis
----

primary cutaneous [[anaplastic large cell lymphoma]]
----

primary cutanoue peripheral T-cell lymphomas, rare subtypes
primary cutaneous γδ T-cell lymphoma
primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma (provisional entity)
primary cutaneous acral CD8+ T-cell lymphoma (provisional entity)
primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (provisional entity)
peripheral T-cell lymphoma, not otherwise specified
angioimmunoblastic T-cell lymphoma and other nodal lymphomas of T follicular helper cell origin
angioimmunoblastic T-cell lymphoma
follicular T-cell lymphoma (provisional entity)
nodal peripheral T-cell lymphoma with T follicular helper phenotype (provisional entity)
anaplastic large-cell lymphoma
----

[[anaplastic large cell lymphoma]], ALK-positive
----

[[anaplastic large cell lymphoma]], ALK-negative
----

breast implant-associated anaplastic large-cell lymphoma (provisional entity)
Hodgkin lymphoma
nodular lymphocyte predominant Hodgkin lymphoma
classical Hodgkin lymphoma
nodular sclerosis classical Hodgkin lymphoma
lymphocyte-rich classical Hodgkin lymphoma
mixed cellularity classical Hodgkin lymphoma
lymphocyte-depleted classical Hodgkin lymphoma
posttransplant lymphoproliferative disorders (PTLD)
plasmacytic hyperplasia PTLD
infectious mononucleosis PTLD
florid follicular hyperplasia PTLD
polymorphic PTLD
monomorphic PTLD
monomorphic B-cell PTLD
monomorphic T/NK-cell PTLD
classical Hodgkin lymphoma PTLD
Histiocytic and dendritic cell neoplasms
histiocytic sarcoma
tumors derived from Langerhans cells
Langerhans cell histiocytosis
Langerhans cell sarcoma
indeterminate dendritic cell tumor
interdigitating dendritic cell sarcoma
follicular dendritic cell sarcoma
inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma
fibroblastic reticular cell tumor
disseminated juvenile xanthogranuloma
Erdheim-Chester disease