Viral vector [Neurosurgery Wiki]

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====== Viral vector ======

Viral [[vector]]s are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). Viruses have evolved specialized molecular mechanisms to efficiently transport their [[genome]]s inside the cells they infect. Delivery of genes by a vector is termed [[transduction]] and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage λ to infect monkey kidney cells maintained in culture.

In addition to their use in molecular biology research, viral vectors are used for [[gene therapy]] and the development of [[vaccine]]s. 

see [[Sendai virus]].

see [[Plasmid]] vector.