Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== Vestigial like family member 4 ====== Vestigial like family member 4 is a [[protein]] that in humans is encoded by the VGLL4 gene. A study indicates that Vestigial like family member 4 [[VGLL4]] is a key player in the mediation of [[NOTCH1]]-dependent HIF1α-regulated erythropoiesis and can be sensitively regulated by [[oxygen]] concentrations. On the other hand, VGLL4 is a pivotal regulator of heme biosynthesis and erythroid terminal differentiation, which collectively improve oxygen metabolism ((Wang Y, Liu X, Xie B, Yuan H, Zhang Y, Zhu J. The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation. Redox Biol. 2019 Sep 2;28:101313. doi: 10.1016/j.redox.2019.101313. [Epub ahead of print] PubMed PMID: 31539803. )). vestigial_like_family_member_4.txt Last modified: 2024/06/07 03:00by 127.0.0.1