Thromboembolism Prevention [Neurosurgery Wiki]

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====== Thromboembolism Prevention ======

[[Thromboembolism]] refers to the obstruction of a blood vessel by a clot that has traveled from another location. Prevention strategies focus on reducing clot formation and include:

===== Pharmacological Prevention =====
  * **Antiplatelet Agents** – Aspirin, Clopidogrel, and other P2Y12 inhibitors prevent platelet aggregation and reduce arterial thrombotic risk.
  * **Anticoagulants** – Warfarin, Heparin, and Direct Oral Anticoagulants (DOACs) like Rivaroxaban and Apixaban are used to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE).
  * **Low Molecular Weight Heparin (LMWH)** – Enoxaparin is commonly used in hospitalized patients to prevent venous thromboembolism (VTE).

===== Non-Pharmacological Prevention =====
  * **Compression Stockings** – Reduce the risk of DVT in post-surgical and immobile patients.
  * **Early Mobilization** – Encouraging movement after surgery or hospitalization to prevent venous stasis.
  * **Intermittent Pneumatic Compression (IPC)** – Devices that inflate and deflate around the legs to promote circulation.

===== Deep-Vein Thrombosis Prophylaxis =====
[[Deep-Vein Thrombosis Prophylaxis]]