Therapeutic Enthusiasm [Neurosurgery Wiki]

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====== Therapeutic Enthusiasm ======

Therapeutic [[enthusiasm]] refers to the premature or exaggerated [[optimism]] about the clinical potential of a treatment or molecular target, often based on limited, early-stage, or preclinical evidence.

🧪 In research contexts:
It usually manifests when authors or scientists:

Overstate the translational relevance of a molecular finding

Propose therapeutic applications without sufficient validation in humans

Ignore biological complexity, safety, or feasibility

⚠️ Why it's problematic:
Therapeutic enthusiasm can:

Mislead readers, funders, or clinicians

Fuel hype cycles that later collapse

Undermine [[scientific credibility]] when results fail to translate

In short: Therapeutic enthusiasm turns a petri dish into a miracle cure—on paper.