Subjective Cognitive Decline [Neurosurgery Wiki]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
====== Subjective Cognitive Decline ======

In [[memory]] clinics, patients with significant memory complaints without objective neuropsychological findings are common. They are classified as Subjective [[Cognitive Decline]] (SCD) and, as a group, face a heightened risk for future [[dementia]]. However, the SCD group is heterogeneous and comprises patients suffering from a somatoform condition, namely [[Functional Cognitive Disorder]] (FCD). These patients make up at least 11 % of memory clinics' attendees. The aim of a long-term follow-up study was to investigate if patients diagnosed with FCD also face a higher risk of developing dementia.

42 Patients were recruited at a university hospital memory clinic. FCD was diagnosed according to the Schmidtke criteria (see table 1). Ten years later, all were invited again. Participants were interviewed, screened for depression and given neuropsychological tests of verbal memory and information processing speed. Cognitive impairment was defined as performance below 1.5 standard deviations (SD) of the age-related mean.

28 of 42 patients (67 %) took part in this follow-up. The group's mean results in both cognitive measures were stable over time. All individual performances were within 1.5 SD. With ten patients (24 %) brief contact was successful and manifest dementia could be excluded. Four patients (10 %) could not be contacted.

In retrospect, the Schmidtke criteria for FCD safely identified memory clinic attendees with SCD who did not proceed to MCI or dementia. None of the patients who could be contacted for this follow-up after a decade (90 % of baseline participants) showed signs of dementia
((Nora S, Stefan K, Klaus S, Birgitta M. Functional Cognitive Disorder in Subjective Cognitive Decline - A ten-year follow-up. Int J Geriatr Psychiatry. 2020 Nov 9. doi: 10.1002/gps.5466. Epub ahead of print. PMID: 33166421.)).
----
Fujishiro H, Ota K, Yamagata M, Nagahama Y. A patient with [[subjective cognitive decline]] and recurrent dream-enactment behaviours in a memory clinic: potential diagnostic utility of cardiac 123 I-[[metaiodobenzylguanidine]] scintigraphy. Psychogeriatrics. 2020 Oct 28. doi: 10.1111/psyg.12599. Epub ahead of print. PMID: 33118258.