Saffron [Neurosurgery Wiki]

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====== Saffron ======

[[Saffron]] supplementation as a treatment for improving [[sleep quality]] have promising clinical application as its great improvement on all efficacy [[outcome]]s and no serious [[adverse event]]s occurred as the dose was increased. The dose of 100 mg saffron supplementation per day was proved to achieve excellent and more stable curative effect on improving sleep quality in a subgroup analysis. However, further [[investigation]] is necessary to confirm the [[efficacy]] and long-term [[safety]] of different doses of saffron for [[insomnia]].
((Lian J, Zhong Y, Li H, Yang S, Wang J, Li X, Zhou X, Chen G. Effects of
saffron supplementation on improving [[sleep quality]]: a meta-analysis of
randomized controlled trials. Sleep Med. 2022 Mar 6;92:24-33. doi:
10.1016/j.sleep.2022.03.001. Epub ahead of print. PMID: 35325766.)).
----


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