Rhino-Orbital-Cerebral Mucormycosis Treatment [Neurosurgery Wiki]

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====== Rhino-Orbital-Cerebral Mucormycosis Treatment ======

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=== 1. Surgical Intervention ===
  * **[[Debridement]]:** Aggressive removal of necrotic tissue.
  * **[[Orbital Exenteration]]:** Required in severe cases to prevent intracranial spread.

=== 2. Antifungal Therapy ===
  * **Liposomal [[Amphotericin B]]:** First-line therapy (5–10 mg/kg/day).
  * **Step-Down Therapy:** [[Posaconazole]] or [[Isavuconazole]] for long-term management.

=== 3. Managing Underlying Conditions ===
  * Tight control of blood [[glucose]] levels.
  * Reduce or discontinue [[corticosteroid]]s.

=== 4. Supportive Care ===
  * Oxygen therapy for [[hypoxia]].
  * Fluid and [[electrolyte]] management.