Rheumatoid arthritis (RA) [Neurosurgery Wiki]

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====== Rheumatoid arthritis (RA) ======

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Chronic, systemic [[inflammatory disorder]] that primarily affects [[joint]]s.

===== Epidemiology =====

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease affecting approximately 1% of the global population, with a higher prevalence in women than in men. 
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===== Grading =====

see [[Ranawat Criterion]].
===== Etiology =====

The cause of RA is not completely understood.

Chronic [[inflammation]] and [[oxidative stress]] play pivotal roles in the pathogenesis of RA
===== Clinical features =====

It may result in deformed and painful joints, which can lead to loss of function. The disease may also have signs and symptoms in organs other than joints.

More than 85% of patients with moderate or severe rheumatoid arthritis (RA) have radiographic evidence of C-spine involvement
((Ranawat CS, O'Leary P, Pellicci P, et al. Cervical Spine Fusion in Rheumatoid Arthritis. J Bone Joint Surg. 1979; 61A:1003–1010)).

===== Diagnosis =====

[[Rheumatoid arthritis diagnosis]]




===== Treatment =====

see [[Rheumatoid arthritis Treatment]].

===== Complications ======

see [[Rheumatoid arthritis complications]]

===== Case series =====

[[Rheumatoid arthritis case series]].