🎭 Radiogenomic Theater [Neurosurgery Wiki]

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===== 🎭 Radiogenomic Theater =====

**Definition:**  
A term used to describe the increasingly common practice of combining advanced imaging (radiomics) and genomic data to produce impressive-looking studies that promise clinical transformation — but deliver little beyond glossy figures, moderate AUCs, and speculative conclusions.

**Characteristics:**
  * Overuse of **deep learning** models without external validation  
  * Ambiguous clinical endpoints masked by **heatmaps and pipelines**  
  * Conclusions inflated to justify **grants or headlines**  
  * Real-world applicability: **close to zero**  
  * Frequently published in journals chasing **translational buzzwords**

**Translation:**  
> *Science that performs better on posters than in practice. It looks like progress, sounds like innovation — but doesn’t change how we treat patients.*