Pulmonary embolism treatment [Neurosurgery Wiki]

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====== Pulmonary embolism treatment ======

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If the diagnosis is seriously entertained, start [[heparin]] – unless contraindicated – without
waiting for the results of diagnostic studies. For an average 70 kg patient, begin with 5000–7500 unit IV
bolus, followed by 1000 U/hr drip (less for smaller patients). Follow [[PTT]] and titrate drip rate for PTT
1.5 to 2 × control.
The use of heparin shortly after surgery and in patients with brain tumors is controversial, and
vena cava interruption may be an alternate consideration (e.g. Greenfield filter).
Patients with massive PEs may be hemodynamically unstable. They usually require ICU care, often
with PA catheter and pressors.