🩺 Practice-Changing [Neurosurgery Wiki]

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====== 🩺 Practice-Changing ======

[[Practice]]-changing refers to:

A study, discovery, or piece of evidence so robust, clinically relevant, and reproducible that it justifies a change in standard clinical practice or treatment guidelines.

🔍 Key Characteristics of Practice-Changing Evidence:

✅ High-quality [[design]] (usually randomized controlled trials or meta-analyses)

✅ Large [[sample size]] and adequate [[statistical power]]

✅ Clinically meaningful outcomes (e.g., survival, quality of life, functional status)

✅ External validity — findings can be generalized across patient populations

✅ Reproducibility — confirmed in multiple independent studies

✅ Often leads to updates in clinical guidelines or standard operating procedures

⚠️ Misuse in Literature:
The term is sometimes misapplied to preliminary or low-quality studies as a form of scientific exaggeration or unjustified enthusiasm, especially in retrospective or industry-funded research.