Platelet aggregation inhibitor [Neurosurgery Wiki]

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=====Platelet aggregation inhibitor=====
The question of whether preoperative platelet aggregation inhibitors must be stopped before elective [[spinal surgery]] has never been answered in the literature. 

In prospective series, it was not found no increase in the risk of postoperative spinal bleeding with the use of [[clopidogrel]] or [[acetylsalicylic acid]]. This finding suggests that [[spine surgery]] can be done without stopping [[anticoagulation]]. Lacking specific [[guideline]]s, each patient should be treated on an individual basis, and the potential benefits of anticoagulation should be compared with the potential risks (risk-benefit ratio)
((Akhavan-Sigari R, Rohde V, Abili M. Continuation of medically necessary
platelet aggregation inhibitors - acetylsalicylic acid and clopidogrel - during
surgery for spinal degenerative disorders: Results in 100 patients. Surg Neurol
Int. 2014 Aug 28;5(Suppl 7):S376-9. doi: 10.4103/2152-7806.139675. eCollection
2014. PubMed PMID: 25289165; PubMed Central PMCID: PMC4173210.
)).