Phthalein dye [Neurosurgery Wiki]

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====== Phthalein dye ======


Phthalein dyes are a class of dyes mainly used as pH indicators, due to their ability to change colors depending on pH.[1] They are formed by the reaction of phthalic anhydride with various phenols. They are a subclass of triarylmethane dyes.

[[Bromsulfthalein]] (also known as bromsulphthalein, bromosulfophthalein, and BSP) is a [[phthalein dye]] used in liver function tests. Determining the rate of removal of the dye from the bloodstream gives a measure of liver function.

Binding of sulfobromophthalein (BSP) sodium and [[indocyanine green]] (ICG) by plasma alpha-1 [[lipoprotein]]s
((Baker KJ. Binding of sulfobromophthalein (BSP) sodium and indocyanine green
(ICG) by plasma alpha-1 lipoproteins. Proc Soc Exp Biol Med. 1966
Aug-Sep;122(4):957-63. PubMed PMID: 5918158.
)).