Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. Patchell Criteria Metastatic epidural spinal cord compression Surgical decompression has proven to be beneficial if a patients meets these criteria: Inclusion Tissue-proven cancer, not of CNS or spinal column origin Radiographic spinal cord displacement >= 1 neurological sign, symptom or pain Single area (one level or multiple contiguous spinal levels) Estimated survival >= 3 months Exclusion Radiosensitive tumors: lymphoma, leukaemia, multiple myeloma, germ-cell tumor Paraplegic >48h for study entry Only cauda or root compression Prior radiation (if study dose of 10x 3Gy is contraindicated) Indication Patients with metastatic epidural spinal cord compression treated with direct (<24h after randomisation) decompressive surgery plus postoperative radiotherapy retain the ability to walk for longer and regain the ability more often than do patients treated with radiotherapy alone. Reference: Patchell et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet (2005) vol. 366 (9486) pp. 643-8 patchell_criteria.txt Last modified: 2024/06/07 02:54by 127.0.0.1