ON-Q [Neurosurgery Wiki]

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====== ON-Q ======

ON-Q* is an elastomeric [[drug delivery system]] that delivers local anesthetic directly to the surgical site either through a nerve block or a surgeon-placed catheter, for post-operative pain relief. It is indicated to significantly reduce the use of [[opioid]]s and to provide better [[pain]] relief than opioids alone.
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Sixty-one patients who underwent ALIF surgery were enrolled. For thirty-one of them, a continuous [[local anesthetic]]s infiltration system was used at the abdominal site. They collected [[data]] regarding the [[patient]]s' [[sleep quality]]; satisfaction with pain control after surgery; abilities to perform physical tasks and the additional application of [[opioid]]s in the postoperative 48 hours.

The [[On-Q]] system group showed reduced [[visual analog scale]] scores for pain at the surgical site during rest and movement at 0, 12, 24, and 48 hours; and more were satisfied with pain control management at the first postoperative day (7.0 ± 1.2 vs. 6.0 ± 1.4; P = 0.003) and week (8.1 ± 1.6 vs. 7.0 ± 1.8; P = 0.010) than the control group. The number of additional patient-controlled analgesia (PCA) bolus and [[pethidine]] injections was lower in the On-Q group (PCA: 3.67 ± 1.35 vs. 4.60 ± 1.88; P = 0.049 and pethidine: 2.09 ± 1.07 vs. 2.73 ± 1.38; P = 0.032). Patients who used the On-Q system performed more diverse activity and achieved earlier [[ambulation]] than those in the control group.

Continuous [[wound infiltration]] with [[ropivacaine]] using an [[On-Q]] system may be effective for controlling [[postoperative pain]] after [[ALIF]] surgery
((Lee SM, Yun DJ, Lee SH, Lee HC, Joeng KH. Continuous [[wound infiltration]] of [[ropivacaine]] for reducing of [[postoperative pain]] after anterior [[lumbar fusion]] surgery: a clinical retrospective comparative study. Korean J Pain. 2021 Apr 1;34(2):193-200. doi: 10.3344/kjp.2021.34.2.193. PMID: 33785671.)).