Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. =====Nitrosourea===== Nitrosoureas represent one of the most active classes of agents in the treatment of [[high grade glioma]]s and [[glioblastoma]]. In clinical practice, the most commonly used compounds are [[lomustine]] (either alone or in combination with [[procarbazine]] and [[vincristine]]), [[carmustine]], and [[fotemustine]]. Given their toxicity profile and subsequent to the introduction of [[temozolomide]] in clinical practice, most of these agents were moved to the recurrent setting ((Brandes AA, Bartolotti M, Tosoni A, Franceschi E. Nitrosoureas in the Management of Malignant Gliomas. Curr Neurol Neurosci Rep. 2016 Feb;16(2):13. doi: 10.1007/s11910-015-0611-8. PubMed PMID: 26750128. )). nitrosourea.txt Last modified: 2024/06/07 02:48by 127.0.0.1