Multiple sclerosis classification [Neurosurgery Wiki]

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====== Multiple sclerosis classification ======

Typically causes exacerbations and remissions in various locations in the CNS (dissemination in space and time). Common symptoms: visual disturbances (diplopia, blurring, field cuts or scotoma), spastic paraparesis, and bladder disturbances. 

===== Category-Definition =====

relapsing-remitting episodes of acute worsening with recovery and a stable course between relapses.

==== Secondary progressive multiple sclerosis ====
[[Secondary progressive multiple sclerosis]]


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primary progressive gradual, nearly continuous neurologic deterioration from the onset of symptoms
progressive relapsing gradual neurologic deterioration from the onset of symptoms, but with subsequent superimposed relapses
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Relapsing-remitting MS is the most common pattern (≥ 70%) at the onset, and has the best response to therapy, but > 50% of cases eventually become secondary progressive MS. Only 10% have primary progressive MS, and these patients tend to be older at onset (40–60 years) and frequently develop progressive myelopathy.

Progressive relapsing MS is very uncommon. Deficits present > 6 months usually persist.