Meningioma histological subtype [Neurosurgery Wiki]

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====== Meningioma histological subtype ======

{{rss>https://pubmed.ncbi.nlm.nih.gov/rss/search/1TCb4A3LOGb0sLC_j25xWSVn_ZM3I6Yc9Q5Sh2dNLFzf2jHMqk/?limit=15&utm_campaign=pubmed-2&fc=20250210062711}}



===== WHO classification =====
[[World Health Organization Classification of Tumors of the Central Nervous System 2016]] describes 15 subtypes of [[meningioma]]. Nine of these subtypes are allotted to WHO grade I, and three each to grade II and grade III. Grading is based solely on histology, with an absence of molecular markers. Although the existing classification and grading approach is of prognostic value, it harbours shortcomings such as ill-defined parameters for subtypes and grading criteria prone to arbitrary judgment
((Sahm F, Schrimpf D, Stichel D, Jones DTW, Hielscher T, Schefzyk S,
Okonechnikov K, Koelsche C, Reuss DE, Capper D, Sturm D, Wirsching HG, Berghoff
AS, Baumgarten P, Kratz A, Huang K, Wefers AK, Hovestadt V, Sill M, Ellis HP,
Kurian KM, Okuducu AF, Jungk C, Drueschler K, Schick M, Bewerunge-Hudler M,
Mawrin C, Seiz-Rosenhagen M, Ketter R, Simon M, Westphal M, Lamszus K, Becker A, 
Koch A, Schittenhelm J, Rushing EJ, Collins VP, Brehmer S, Chavez L, Platten M,
Hänggi D, Unterberg A, Paulus W, Wick W, Pfister SM, Mittelbronn M, Preusser M,
Herold-Mende C, Weller M, von Deimling A. DNA methylation-based classification
and grading system for meningioma: a multicentre, retrospective analysis. Lancet 
Oncol. 2017 May;18(5):682-694. doi: 10.1016/S1470-2045(17)30155-9. Epub 2017 Mar 
15. PubMed PMID: 28314689.)).

{{::meningiomaclassification.jpg|}}

[[Meningothelial meningioma]] 9531/0

[[Fibrous meningioma]] (fibroblastic) 9532/0

[[Transitional meningioma]] (mixed) 9537/0

[[Psammomatous meningioma]] 9533/0

[[Angiomatous meningioma]] 9534/0

[[Microcystic meningioma]] 9530/0

[[Secretory meningioma]] 9530/0

[[Lymphoplasmacyte rich meningioma]] 9530/0

[[Metaplastic meningioma]] 9530/0

[[Chordoid meningioma]] 9538/1

[[Clear cell meningioma]] 9538/1

[[Atypical meningioma]] 9539/1

[[Papillary meningioma]] 9538/3

[[Rhabdoid meningioma]] 9538/3

[[Anaplastic meningioma]] (malignant) 9530/3