Medulloblastoma clinical features [Neurosurgery Wiki]

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====== Medulloblastoma clinical features ======

Clinical history is typically brief (6–12 weeks). The predilection for [[posterior fossa]] predisposes to early [[obstructive hydrocephalus]]. Usual presenting symptoms: H/A, N/V, and [[ataxia]]. Infants with hydrocephalus may present with irritability, lethargy, or progressive [[macrocrania]]
((Park TS, Hoffman HJ, Hendrick EB, et al. Medulloblastoma: Clinical Presentation and Management. J Neurosurg. 1983; 58:543–552)).

Spinal drop metastases may produce [[back pain]], [[urinary retention]], or leg [[weakness]].

Common signs: [[papilledema]], truncal & appendicular [[ataxia]], [[nystagmus]], EOM palsies. Macrocrania in infants and young children.
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[[Medulloblastoma]] may also cause nuclear [[facial palsy]] (from the involvement of [[facial colliculus]] on the floor of the [[fourth ventricle]]).