Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. [[Syrosingopine]], a dual [[MCT1]]/4 inhibitor and old antihypertensive drug with good CNS penetration, showed dose-dependent anti-tumor effects in vitro on [[U87]]MG and [[LN229]] glioma cell lines: Increased cytotoxicity Enhanced apoptosis Reduced migration/invasion Clinical Relevance: MCT1/4 may serve as diagnostic immunohistochemical markers. Syrosingopine may represent a promising adjunctive therapy for GBM ((Behera MM, Purkait S, Ghosh A, Sable MN, Sahu RN, Chhabra G. The [[Monocarboxylate Transporter]]s [[MCT1]] and [[MCT4]] Are Highly Expressed in [[Glioblastoma]] and Crucially Implicated in the [[Pathobiology]]. Neuropathology. 2025 Mar 27. doi: 10.1111/neup.70006. Epub ahead of print. PMID: 40145253.)) mct4.txt Last modified: 2025/03/27 10:42by 127.0.0.1