Lymphoma [Neurosurgery Wiki]

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====== Lymphoma ======

===== General information =====

==== Key concepts ====

● may be primary ([[Primary central nervous system lymphoma]]) or secondary (pathologically identical)

● suspected with homogeneously enhancing lesion(s) in the central gray matter or corpus callosum
(on MRI or CT) especially in AIDS patients

● may present with multiple cranial-nerve palsies

● diagnosis highly likely if tumor seen in conjunction with uveitis

● very responsive initially to steroids → short-lived disappearance (“ghost tumors”)

● treatment: usually XRT ± chemotherapy. Role of neurosurgery usually limited to biopsy and/or
placement of ventricular access reservoir for chemotherapy

● risk factors: immunosuppression (AIDS, transplants), Epstein-Barr virus, collagen vascular diseases

===== Classification =====

[[Lymphoma Classification]].