Low-Grade Glioma diagnosis [Neurosurgery Wiki]

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====== Low-Grade Glioma diagnosis ======

Diagnosis of [[Low-Grade Glioma]]s (LGGs) is made through a combination of [[imaging]], [[histopathology]], and [[molecular]] diagnostic methods. On [[computed tomography]], low-grade gliomas appear as diffuse areas of low [[attenuation]]. On conventional [[magnetic resonance imaging]] (MRI), which is currently the imaging modality of choice, LGGs are often [[homogeneous]] with low [[signal intensity]] on [[T1]]-weighted sequences and [[hyperintensity]] on [[T2]]-weighted and Fluid-Attenuated Inversion Recovery ([[FLAIR]]) sequences.

Despite characteristic radiographic findings, tumor grade cannot be determined by imaging alone. Newer imaging techniques, such as [[MR spectroscopy]] ([[MRS]]) and [[positron emission tomography]] (PET) imaging, may improve the diagnostic potential; however, at this time, histopathologic examination of tissue remains the gold standard for diagnosis and grading of LGG
((Forst DA, Nahed BV, Loeffler JS, Batchelor TT. Low-grade gliomas. Oncologist. 
2014 Apr;19(4):403-13. doi: 10.1634/theoncologist.2013-0345. Epub 2014 Mar 24.
Review. PubMed PMID: 24664484; PubMed Central PMCID: PMC3983820.
)).

===== Magnetic resonance imaging =====

[[Low-Grade Glioma magnetic resonance imaging]]


===== FET PET =====

see [[FET PET for Low-Grade Glioma]] 



===== References =====